Figure 2
From: Weakened Cholinergic Blockade of Inflammation Associates with Diabetes-Related Depression
Depression, inflammation and cholinergic activities increase with age. Depression scores (sum of 9 items of the “Patient Health Questionnaire” (PHQ)), Inflammation (as reflected by the erythrocyte sedimentation rate, ESR, mm/h) and cholinergic enzymatic activities (Cholinergic status, CS, the total capacity for acetylcholine hydrolysis, nmol substrate hydrolyzed/min per ml (19)) all increase with age in both genders. (Statistics: ANOVA of 4 age groups).