Figure 3
From: Weakened Cholinergic Blockade of Inflammation Associates with Diabetes-Related Depression
Longer life expectancy in countries with lower historical pathogen load. (A) Mean mortality rate under 5 years (per 1,000 live births) and (B) life expectancy (data from http://data.worldbank.org/) were plotted against historical pathogen load values based on the presence of nine diseases (leishmanias, schistosomes, trypanosomes, leprosy, malaria, typhus, filariae, dengue and tuberculosis) taken from Murray and Schaller score (13). (C) Countries were divided to three equal parts reflecting escalating values of historical pathogen load. This analysis revealed that the higher the pathogen-load the lower total life expectancy (p < 0.001). (D) To avoid irrelevant death causes (for example, war or famine) we further focused this analysis of life expectancy on countries with mean life expectancy above 70 (p < 0.001). (E) The historical pathogen load and mean mortality under 5 years (per 1,000 live births) scores (p < 0.001).