Skip to main content

Table 2 Cosegregation analysis for representative microsatellite markers within the genomic loci on RNO4, -11 and -13, based on F2 intercross between CDs/y and SBN/y.

From: Three Interacting Genomic Loci Incorporating Two Novel Mutations Underlie the Evolution of Diet-induced Diabetes

        

AUC

    
 

Genomic Locus

1 month DD

2.5 months DD

4 months DD

 

RN04

RNOll

RNG-13

AVG

SEM

N

AVG

SEM

 

AVG

SEM

N

1

NN

SS

NN

30458

819

18

35934

2081

18

38328

1874

18

2

SN

SS

SN/NN

         
 

NN

SS

SN

35057

830

74

40972

1095

72

40387

1190

70

3

SN/NN

SS

SS

39909

1316

30

49524

1492

30

48413

1444

30

4

SS

SS

SN/NN

44267

1303

28

50745

1637

28

46502

1143

25

5

SS

SS

SS

46918

2125

14

53861

2070

13

53854

2114

13

 

ANOVA

 

F

 

21.01

  

16.75

  

11.30

 
   

P

 

0.0000

  

0.0000

  

0.0000

 
 

Post hoc

 

1 vs 2

 

0.0120

  

0.0315

  

0.3767

 
 

LSD test

 

1 vs 3

 

0.0000

  

0.0000

  

0.0002

 
   

1 vs 4

 

0.0000

  

0.0000

  

0.0031

 
   

1 vs 5

 

0.0000

  

0.0000

  

0.0000

 
   

2 vs 3

 

0.0014

  

0.0000

  

0.0000

 
   

2 vs 4

 

0.0000

  

0.0000

  

0.0033

 
   

2 vs 5

 

0.0000

  

0.0000

  

0.0000

 
   

3 vs 4

 

0.0172

  

0.5986

  

0.4230

 
   

3 vs 5

 

0.0020

  

0.1400

  

0.0641

 
   

4 vs 5

 

0.2413

  

0.2932

  

0.0155

 
  1. Data are presented for three loci interaction, as the mean (AVG) of the area under the curve (AUC) after 1, 2.5 and 4 months of DD, grouped by genotypes RR, SN and NN. Group average were compared by one-way ANOVA, providing F and p values; post hoc analysis was performed using the least significant difference (LSD) test. SS, homozygous for CDs/y; SN, heterozygous; NN, homozygous for SBN/y.