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Figure 2 | Molecular Medicine

Figure 2

From: Excessive Reversal of Epidermal Growth Factor Receptor and Ephrin Signaling Following Tracheal Occlusion in Rabbit Model of congenital Diaphragmatic Hernia

Figure 2

Surgical Model of CDH and CDH/TO. (A) The intact left diaphragm of an E30.5 rabbit fetus. (B) The disrupted left diaphragm of a diaphragmatic hernia (DH) fetus. (C) Normal size of the right lung (RL) and left lung (LL) in a control E30.5 rabbit fetus. (D) Herniation of abdominal contents into the left chest in DH resulted in lung hypoplasia and displacement of thoracic organs to the right. (E) Tracheal occlusion (TO) after DH increased lung size, resolved the rightward shift and reduced herniation of abdominal contents into the thorax. (G) TO alone increased lung size beyond that of control.

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Molecular Medicine

ISSN: 1528-3658