Figure 3
Age-dependent analysis of Aβ deposition and Aβ levels in AD/TTR+/− mice, control or treated with resveratrol. Analyzing the results in an age-dependent manner, we observed that Aβ plaque burden (left axis) and brain detergent-soluble Aβ42 levels (right axis) had a tendency to decrease along with lower age. As for the FA-soluble fraction, we observed that for the older mouse, the treatment did not confer any protection, showing even higher levels than the average of the control group.