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Figure 4 | Molecular Medicine

Figure 4

From: Anti-LRP/LR-Specific Antibody IgG1-iS18 Significantly Impedes Adhesion and Invasion in Early- and Late-Stage Colorectal Carcinoma Cells

Figure 4

(A) Detection of total 37 kDa LRP levels in protein lysates of MCF-7, SW-480, HT-29 and DLD-1 cells. IgG1-iS18 was used as the primary antibody, with HRP-coupled secondary antibody; 42kDa β-actin was used as a loading control. (B) Densitometric analysis of total LRP/LR levels on SW-480, HT-29 and DLD-1 cell lines revealed that, compared to MCF-7, DLD-1 contained the most total LRP/LR, displaying a 3.5-fold increase. A significant two-fold increase in total LRP/LR levels between early- and late-stage colorectal cancer was also found. These data represent experiments performed in triplicate using different cell cultures.

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Molecular Medicine

ISSN: 1528-3658