Skip to main content
Figure 6 | Molecular Medicine

Figure 6

From: Anti-LRP/LR-Specific Antibody IgG1-iS18 Significantly Impedes Adhesion and Invasion in Early- and Late-Stage Colorectal Carcinoma Cells

Figure 6

Invasion of ECM-like Matrigel™ by tumorigenic cell lines. Each cell line’s untreated cells were compared with MCF-7 untreated control cells to determine invasive potential. P values show that all three colorectal cancer cell lines had an increase in invasive potential compared to MCF-7. After treatment with the anti-LRP/LR-specific antibody, P values showed significantly decreased adhesive potential compared to MCF-7 control cells: SW-480 by 54%, HT-29 by 60% and DLD-1 by 69%. The control antibody IgG1-HD37 did not affect the invasive potential of the tumorigenic cell lines as expected.

Back to article page

Molecular Medicine

ISSN: 1528-3658