Figure 2

Dabigatran monotherapy is associated with angiogenesis and tumor cell proliferation. (A) H&E-stained pancreatic cancer sections obtained from placebo or dabigatran-treated mice. Representative pictures were taken at magnification of 200 ×, * indicates tumor tissue and arrow indicates red blood cells. (B and C) Paraffin sections obtained from placebo or dabigatran-treated mice stained for (B) CD-31 (blood vessel formation) and (C) Ki-67 (proliferation). Right panels show quantifications of the sections depicted in the left panels. Representative pictures were taken at 200 × magnification.