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Table 1 Patient and tumor characteristics.

From: A New Gene Expression Signature for Triple-Negative Breast Cancer using Frozen Fresh Tissue before Neoadjuvant chemotherapy

 

All patients, n = 54

 

TNBC, n = 25

 

nTNBC, n = 25

P value

Age at diagnosis (years)

49

26–71

51

39–71

47

26–61

0.1e

Body mass index (kg/m2)

28.7

20.7–40.1

27.58

20.78–38.01

29.31

21.83 a 39.65

0.14e

<25

9

17%

4

16%

4

16%

0.67f

≥25

38

70%

17

68%

19

76%

0.75f

Menopause status

       

Pre

27

50%

12

48%

13

52%

1f

Post

27

50%

13

52%

12

48%

1f

Background cancera

       

Yes

26

48%

14

56%

10

40%

0.4f

No

28

52%

11

44%

15

60%

0.4f

Diabetes mellitusb

       

Yes

6

11%

5

20%

1

4%

0.2f

No

48

89%

20

80%

24

96%

0.2f

Glucose levels (mg/dl)

104.84

82–193

106.62

88–183

103.67

82–193

0.64e

Number of childrenc

       

Nulliparous

4

7%

1

4%

3

12%

0.6f

1–2

16

30%

8

32%

7

28%

1f

>3

33

61%

16

64%

15

60%

1

Lactationd

       

Yes

22

41%

10

40%

11

44%

1f

No

15

28%

8

32%

6

25%

0.75f

Smoking

       

Yes

8

15%

2

8%

5

20%

0.42f

No

45

83%

22

88%

20

80%

0.7f

TNM

       

T1

1

2%

0

0%

1

4%

1f

T2

25

46%

12

48%

11

44%

1f

T3

16

30%

8

32%

6

25%

0.75f

T4

11

20%

4

16%

7

28%

0.75f

N0

8

15%

3

12%

5

20%

0.5f

N1

32

59%

14

56%

16

64%

0.77f

N2

12

22%

6

24%

4

16%

0.72f

N3

2

4%

2

8%

0

0%

0.47f

M0

54

100%

25

100%

25

100%

1f

Clinical stage

       

I

1

2%

0

0%

1

2%

1f

II

25

46%

12

48%

12

48%

0.78f

III

28

52%

13

52%

12

48%

1f

  1. aAt least one relative (first, second, or third grade).
  2. bConfirmed at BC diagnosis.
  3. cNumber of pregnancies.
  4. dAt least 6 months.
  5. eT test, confidence level at 95%.
  6. fZ test, confidence level at 95%.