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Figure 5 | Molecular Medicine

Figure 5

From: Binding of CLL Subset 4 B Cell Receptor Immunoglobulins to Viable Human Memory B Lymphocytes Requires a Distinctive IGKV Somatic Mutation

Figure 5

Sequences of the IGHV-D-J and IGKV-J rearrangements of subset 4 IGs and of the various IGHV4-34 and IGKV2-30 point revertants. The (A) IGHV4-34- and (B) IGKV2-30-encoded parts of the IG H and L variable domains of CLL subset 4 mAbs (nos. 240, 342 and 183) are aligned with the corresponding germline counterpart. H and L chain revertants are indicated by arrows.

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Molecular Medicine

ISSN: 1528-3658