Fig. 2
From: Inhibition of Protein Phosphatase 1 Stimulates Secretion of Alzheimer Amyloid Precursor Protein
Stimulation of APP S production from COS-1 cells, in response to treatment with phosphatase inhibitors, measured with antibody 22C11
(A) Immunoblot analysis of COS-1 cells treated with the indicated concentrations of OA (10−9–10−6 M okadaic acid) or CA (10−10–10−7 M calyculin A; higher concentrations of calyculin A were toxic). C, control without drug treatment. (B) Quantitation of the dose response from several experiments. The values plotted are the mean ± SEM.