Table 1 Binding parameters of wild-type and mutant ET-1/AngII receptors for AngII and ET-1 expressed in permanent Cosl cell transfectants
From: Molecular Characterization of a Dual Endothelin-1/Angiotensin II Receptor
ET-1/AngII Receptor | KH ET-1 (nmol/L) | KH AngII (nmol/L) | Bmax for AngII (fmols 10−6 cells) |
|---|---|---|---|
Wild type | 0.28 ± 0.07 | 1.30 ± 0.30 | 5.03 ± 0.99 |
R64G | No binding | 1.20 ± 0.13 | 0.95 ± 0.07 |
W65G | No binding | 7.36 ± 1.50 | 4.69 ± 0.84 |