Skip to main content

Retraction Note: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity

The Original Article was published on 01 November 2010

Retraction Note to: Mol Med (2010) 16:479–490

The Editors-in-Chief have retracted this article (Antoine et al. 2010a) following an investigation by the University of Liverpool. The investigation concluded that data contained in this article demonstrate evidence of data manipulation and figure fabrication relating to both western blot and mass-spectrometry data and are therefore unreliable. In Fig. 2a, the blot is duplicated, cut out and flipped vertically from a blot published in Fig. 1 in the following article (Antoine et al. 2010b). In Fig. 3a, lanes in the blot have been selectively cut out and flipped horizontally between the top and bottom blot. In Fig. 5, there are inconsistencies between the stated peak masses and the x-axis. The co-authors of the article were found by the investigation not to be complicit in any research misconduct, and they have been invited to resubmit a revised version of the manuscript for further peer review. More information on the university's investigation can be found on the university website (Further update on research misconduct investigation 2020).

All authors agree to this retraction.


Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Daniel James Antoine.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Antoine, D.J., Williams, D.P., Kipar, A. et al. Retraction Note: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity. Mol Med 26, 130 (2020).

Download citation

  • Published:

  • DOI: