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Anthony Cerami Award in Translational Medicine

About

Molecular Medicine has established the Anthony Cerami Award in Translational Medicine to honor investigators who have created the fundamental innovation necessary for molecular medicine to advance into clinical practice.  The award recognizes leading edge discoveries that have led to improvement of human health, and have opened the door to new therapeutic advances and understanding.

Recipients are investigators who provided the crucial early insight and ideas that are the essence of discovery, creating new fields and research trajectories followed by the persistent clinical investigation that ultimately changes how disease is prevented, diagnosed, and treated. The award celebrates and commemorates the unique attributes of insight, genius, and perseverance that are at the heart of the discovery process.

The recipient receives a $20,000 USD award, and is invited to publish a monograph of their work that inspired or produced the clinical product(s). The monograph represents a unique opportunity to capture the inspirations, insights, surprises, and conceptual advances that are woven into the history of these discoveries, but if left untold, may be lost from the permanent record.

True innovators in medicine and health care are rare, and their stories even more precious.  The Anthony Cerami Award monographs will provide sources of inspiration and insight to subsequent generations, by providing the stories behind the pioneering advances.  The monographs will be written in the first person as an account of the personal experience behind the scientific research. As described in a narrative format, these articles will provide insight into the driving forces that were at work, the decision points, the scientific/political/social climate, and the key results that changed the future.

Monographs, in the voice of the discoverer, will permanently document their stories and inspire future innovators to advance medicine.

The Anthony Cerami Award in Translational Medicine - an Editorial by Kevin J Tracey, MD

Cerami Award winner 2017

Sir Paul Nurse, PhD © Fiona Hanson/AP ImagesA Journey in Science: Cell-Cycle Control

The seventh Anthony Cerami Award in Translational Medicine was awarded to Sir Paul Nurse, PhD, director of The Francis Crick Institute. The award is in recognition of his research, which identified protein molecules that control the division (duplication) of cells in the cell cycle currently being examined as a therapy to stop or prevent cancer cell growth.

In his monograph, Dr Nurse’s writes about how his research led to the critical discovery that the protein, cyclin-dependent protein kinase (CDK), found both in yeast and in human genes, controls the cell cycle or cell growth process. Knowledge of the cell cycle is critical to the treatment of cancer. Most cancers are caused by the uncontrolled cell division due to damage to the controls regulating cell growth and reproduction, or by damage to how the cell replicates and grows. Leading drug companies are utilizing the understanding of the role that CDK plays in cell growth to test new therapies to stop cancer cell growth.

“It is an honor to be recognized as an Anthony Cerami Award winner for my work on CDK and its impact on cancer,” said Dr Nurse. “When deciding on a course of study, it has been my belief that it is essential to tackle a significant research problem, one that if solved could make a difference. I’m happy to tell my story to inspire investigators on their path to making a difference.”

Find out more.

2017 Journal Metrics

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